human PCDH19 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PCDH19.
shAAV-218327
AAV-h-PCDH19-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PCDH19 (protocadherin 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EFMR; EIEE9; protocadherin-19
Description (eCommerce)
Protocadherin-19 (PCDH19) is a potential calcium-dependent cell-adhesion protein [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TAB3].
Description (Vector)
PCDH19 is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
57526
Gene Name (eCommerce)
protocadherin 19
Gene Name (Vector)
protocadherin 19
Gene Symbol
PCDH19
HGNC ID
HGNC:14270
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1809
ORF Size (bp)
1809 bp
Protein Name (eCommerce)
Protocadherin-19
RefSeq ID
NM_020766
RefSeq Synonyms
NM_020766, NM_001184880, NM_001105243, BC136628,
Research Areas
Epilepsy,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology
Species
human
Target Sentence
Protocadherin-19 (PCDH19) is a potential calcium-dependent cell-adhesion protein [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TAB3].
UniGene ID
Hs.4993
UniProt ID (eCommerce)
Q8TAB3
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.