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human PCDH11Y shRNA silencing AAV

Name 
AAV-h-PCDH11Y-shRNA
Cat No 
shAAV-218320
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PCDH11Y.

shAAV-218320
AAV-h-PCDH11Y-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PCDH11Y (protocadherin 11 Y-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PCDH-PC; PCDH22; PCDHX; PCDHY
Description (Vector)
PCDH11Y belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.
Gene ID
83259
Gene Name (Vector)
protocadherin 11 Y-linked
Gene Symbol
PCDH11Y
HGNC ID
HGNC:15813
ORF Size (aa)
4020
ORF Size (bp)
4020 bp
RefSeq ID
NM_032971
RefSeq Synonyms
NM_032973, NM_032972, NM_032971, NM_001278619, BC152897,
Species
human
UniGene ID
Hs.661308

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.