human PCDH11X shRNA silencing AAV

Name
AAV-h-PCDH11X-shRNA

Cat No
shAAV-218319

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PCDH11X.

shAAV-218319

AAV-h-PCDH11X-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PCDH11X (protocadherin 11 X-linked). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PCDH-X; PCDH11; PCDHX; PPP1R119

Description (Vector)

PCDH11X belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with variable cytoplasmic domains.

Gene ID

27328

Gene Name (Vector)

protocadherin 11 X-linked

Gene Symbol

PCDH11X

HGNC ID

HGNC:8656

ORF Size (aa)

4014

ORF Size (bp)

4014 bp

RefSeq ID

NM_014522

RefSeq Synonyms

NM_032969, NM_032968, NM_032967, NM_014522, NM_001168363, NM_001168362, NM_001168361, NM_001168360, BC167817,

Species

human

UniGene ID

Hs.655673

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.