human PBXIP1 shRNA silencing AAV

Name
AAV-h-PBXIP1-shRNA

Cat No
shAAV-218302

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PBXIP1.

shAAV-218302

AAV-h-PBXIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PBXIP1 (PBX homeobox interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hematopoietic PBX-interacting protein; HPIP; pre-B-cell leukemia homeobox interacting protein 1; pre-B-cell leukemia transcription factor-interacting protein 1

Description (eCommerce)

Hematopoietic PBX-interacting protein (HPIP) was identified in a yeast two-hybrid screen for factors that interact with PBX1, a homeodomain protein that regulates gene transcription during development and differentiation. Recently, HPIP has been reported to interact with estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) and modulate ER target gene expression.

Gene ID

57326

Gene Name (eCommerce)

PBX homeobox interacting protein 1

Gene Name (Vector)

PBX homeobox interacting protein 1

Gene Symbol

PBXIP1

HGNC ID

HGNC:21199

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2196

ORF Size (bp)

2196 bp

Protein Name (eCommerce)

Pre-B-cell leukemia transcription factor-interacting protein 1

RefSeq ID

NM_020524

RefSeq Synonyms

NM_020524, NM_001317735, NM_001317734, BC016852,

Research Areas

Cytoskeleton,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

Hematopoietic PBX-interacting protein (HPIP) was identified in a yeast two-hybrid screen for factors that interact with PBX1, a homeodomain protein that regulates gene transcription during development and differentiation. Recently, HPIP has been reported to interact with estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) and modulate ER target gene expression.

UniGene ID

Hs.505806

UniProt ID (eCommerce)

Q96AQ6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.