human RNF5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNF5.
shAAV-218292
AAV-h-RNF5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNF5 (ring finger protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E3 ubiquitin-protein ligase RNF5; HsRma1; protein G16; ram1 homolog; RING finger protein 5; ring finger protein 5, E3 ubiquitin protein ligase; RING5; RING-type E3 ubiquitin transferase RNF5; RMA1
Description (eCommerce)
RNF5 (ring finger protein 5) is a membrane-bound E3 ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions [taken from NCBI Entrez Gene (Gene ID: 6048)].
Description (Vector)
RNF5 contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
Gene ID
6048
Gene Name (eCommerce)
ring finger protein 5
Gene Name (Vector)
ring finger protein 5
Gene Symbol
RNF5
HGNC ID
HGNC:10068
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
543
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RNF5
RefSeq ID
NM_006913
RefSeq Synonyms
NM_006913, BC148255, BC127652, BC127651, BC119742, BC119741, BC111392, BC004155,
Research Areas
Mitochondrion,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RNF5 (ring finger protein 5) is a membrane-bound E3 ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions [taken from NCBI Entrez Gene (Gene ID: 6048)].
UniGene ID
Hs.718462
UniProt ID (eCommerce)
Q99942
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.