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human PARVB shRNA silencing AAV

Name 
AAV-h-PARVB-shRNA
Cat No 
shAAV-218253
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PARVB.

shAAV-218253
AAV-h-PARVB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PARVB (parvin beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-56
Description (Vector)
PARVB encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
29780
Gene Name (Vector)
parvin beta
Gene Symbol
PARVB
HGNC ID
HGNC:14653
ORF Size (aa)
1095
ORF Size (bp)
1095 bp
RefSeq ID
NM_013327
RefSeq Synonyms
NM_013327, NM_001243386, NM_001243385, NM_001003828, BC046103,
Species
human
UniGene ID
Hs.475074

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.