human PAK1IP1 shRNA silencing AAV

Name 
AAV-h-PAK1IP1-shRNA
Cat No 
shAAV-218152
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PAK1IP1.

shAAV-218152
AAV-h-PAK1IP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PAK1IP1 (PAK1 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA421M1.5; hPIP1; MAK11; p21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; PAK1-interacting protein 1; PIP1; WD repeat-containing protein 84; WDR84
Description (eCommerce)
PIP1/WDR84 (PAK1IP1) was identified as a p21-activated protein kinase (PAK) interacting protein that functions as a negative regulator of PAK activity and PAK signaling pathways. PIP1/WDR84 (PAK1IP1) contains 5 G beta-like WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation.
Gene ID
55003
Gene Name (eCommerce)
PAK1 interacting protein 1
Gene Name (Vector)
PAK1 interacting protein 1
Gene Symbol
PAK1IP1
HGNC ID
HGNC:20882
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1179
ORF Size (bp)
1179 bp
Protein Name (eCommerce)
p21-activated protein kinase-interacting protein 1
RefSeq ID
NM_017906
RefSeq Synonyms
NM_017906, BC010907,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
PIP1/WDR84 (PAK1IP1) was identified as a p21-activated protein kinase (PAK) interacting protein that functions as a negative regulator of PAK activity and PAK signaling pathways. PIP1/WDR84 (PAK1IP1) contains 5 G beta-like WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation.
UniGene ID
Hs.310231
UniProt ID (eCommerce)
Q9NWT1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.