human PAH shRNA silencing AAV

Name 
AAV-h-PAH-shRNA
Cat No 
shAAV-218145
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PAH.

shAAV-218145
AAV-h-PAH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PAH (phenylalanine hydroxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PH; PKU; PKU1
Description (Vector)
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
Gene ID
5053
Gene Name (Vector)
phenylalanine hydroxylase
Gene Symbol
PAH
HGNC ID
HGNC:8582
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_000277
RefSeq Synonyms
NM_000277, BC026251,
Species
human
UniGene ID
Hs.643451

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.