human PABPC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PABPC1.
shAAV-218091
AAV-h-PABPC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PABPC1 (poly(A) binding protein cytoplasmic 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAB1; PABP; PABP1; PABPC2; PABPL1
Description (Vector)
PABPC1 encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
Gene ID
26986
Gene Name (Vector)
poly(A) binding protein cytoplasmic 1
Gene Symbol
PABPC1
HGNC ID
HGNC:8554
ORF Size (aa)
1911
ORF Size (bp)
1911 bp
RefSeq ID
NM_002568
RefSeq Synonyms
NM_002568, BC023520, BC015958,
Species
human
UniGene ID
Hs.387804
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.