human OSGIN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OSGIN1.
shAAV-217961
AAV-h-OSGIN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OSGIN1 (oxidative stress induced growth inhibitor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDGI; OKL38
Description (Vector)
OSGIN1 encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product.
Gene ID
29948
Gene Name (Vector)
oxidative stress induced growth inhibitor 1
Gene Symbol
OSGIN1
HGNC ID
HGNC:30093
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_013370
RefSeq Synonyms
NM_182981, NM_182980, NM_013370, BC113417, BC093687, BC032476,
Species
human
UniGene ID
Hs.128055
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.