human OSCAR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OSCAR.
shAAV-217958
AAV-h-OSCAR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OSCAR (osteoclast associated, immunoglobulin-like receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PIgR-3; PIGR3
Description (Vector)
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
126014
Gene Name (Vector)
osteoclast associated, immunoglobulin-like receptor
Gene Symbol
OSCAR
HGNC ID
HGNC:29960
ORF Size (aa)
849
RefSeq ID
NM_130771
RefSeq Synonyms
NM_206818, NM_133169, NM_133168, NM_130771, NM_001282350, NM_001282349, BC035023,
Species
human
UniGene ID
Hs.347655
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.