human OSBPL9 shRNA silencing AAV

Name 
AAV-h-OSBPL9-shRNA
Cat No 
shAAV-217957
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OSBPL9.

shAAV-217957
AAV-h-OSBPL9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OSBPL9 (oxysterol binding protein like 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
71
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ORP9; ORP-9; OSBP-related protein 9; oxysterol-binding protein-related protein 9
Description (eCommerce)
Oxysterol-binding protein-related protein 9 (OSBPL9) is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function [taken from NCBI Entrez Gene (Gene ID: 114883)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96SU4].
Description (Vector)
OSBPL9 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.
Gene ID
114883
Gene Name (eCommerce)
oxysterol binding protein like 9
Gene Name (Vector)
oxysterol binding protein like 9
Gene Symbol
OSBPL9
HGNC ID
HGNC:16386
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
Protein Name (eCommerce)
Oxysterol-binding protein-related protein 9
RefSeq ID
NM_024586
RefSeq Synonyms
NM_148909, NM_148908, NM_148907, NM_148906, NM_148905, NM_148904, NM_024586, NM_001330580, BC025978,
Research Areas
Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Oxysterol-binding protein-related protein 9 (OSBPL9) is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function [taken from NCBI Entrez Gene (Gene ID: 114883)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96SU4].
UniGene ID
Hs.21938
UniProt ID (eCommerce)
Q96SU4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.