human OSBP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OSBP2.
shAAV-217944
AAV-h-OSBP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OSBP2 (oxysterol binding protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HLM; ORP-4; ORP4; OSBPL1; OSBPL4
Description (Vector)
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.
Gene ID
23762
Gene Name (Vector)
oxysterol binding protein 2
Gene Symbol
OSBP2
HGNC ID
HGNC:8504
ORF Size (aa)
2748
ORF Size (bp)
2748 bp
RefSeq ID
NM_030758
RefSeq Synonyms
NM_030758, NM_001282742, NM_001282741, NM_001282740, NM_001282739, NM_001282738, BC118914,
Species
human
UniGene ID
Hs.517546
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.