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human OS9 shRNA silencing AAV

Name 
AAV-h-OS9-shRNA
Cat No 
shAAV-217940
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OS9.

shAAV-217940
AAV-h-OS9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OS9 (OS9, endoplasmic reticulum lectin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ERLEC2; OS-9
Description (Vector)
OS9 encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
10956
Gene Name (Vector)
OS9, endoplasmic reticulum lectin
Gene Symbol
OS9
HGNC ID
HGNC:16994
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
RefSeq ID
NM_006812
RefSeq Synonyms
NM_006812, NM_001261423, NM_001261422, NM_001261421, NM_001261420, NM_001017958, NM_001017957, NM_001017956, BC023513, BC007254, BC000532,
Species
human
UniGene ID
Hs.527861

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.