human EIF4B Over-expression AAV

Name 
AAV-h-EIF4B
Cat No 
AAV-207774
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EIF4B.

AAV-207774
AAV-h-EIF4B

Ready-to-use AAV expressing Human EIF4B (eukaryotic translation initiation factor 4B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EIF-4B; eukaryotic translation initiation factor 4B; PRO1843
Description (eCommerce)
Eukaryotic initiation factor 4B (eIF4B) is a factor required for the binding of mRNA to ribosomes for the initiation of translation. eIF4B has been demonstrated to modulate the helicase activity of eIF4A, a component of the eIF4F complex.
Gene ID
1975
Gene Name (eCommerce)
eukaryotic translation initiation factor 4B
Gene Name (Vector)
eukaryotic translation initiation factor 4B
Gene Symbol
EIF4B
HGNC ID
HGNC:3285
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1836
ORF Size (bp)
1836 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 4B
RefSeq ID
NM_001417
RefSeq Synonyms
NM_001417, NM_001330654, NM_001300821, BC098437, BC073154, BC073139,
Research Areas
Cancer,Gene Expression,IFN Signaling,IGF-1 Signaling,Insulin Signaling,Metabolism/Metabolic Process,mRNA Binding,mTOR Signaling,PI3K/Akt Signaling,RNA Binding,RNA Processing,RNA Transport,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,immunology,metabolism,signal_transduction
Species
human
Target Sentence
Eukaryotic initiation factor 4B (eIF4B) is a factor required for the binding of mRNA to ribosomes for the initiation of translation. eIF4B has been demonstrated to modulate the helicase activity of eIF4A, a component of the eIF4F complex.
UniGene ID
Hs.702041
UniProt ID (eCommerce)
P23588

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.