human OBFC2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NABP2.
shAAV-217320
AAV-h-OBFC2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NABP2 (nucleic acid binding protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hSSB1; LP3587; Nucleic acid-binding protein 2; OBFC2B; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
Description (eCommerce)
Single-stranded DNA -binding protein (SSB1) is phosphorylated by ATM in response to DNA damage. SSB1 is required for checkpoint activation and is critical for genomic stability.
Description (Vector)
Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 (PubMed 18449195)).(supplied by OMIM, Jun 2008)
Gene ID
79035
Gene Name (eCommerce)
nucleic acid binding protein 2
Gene Name (Vector)
nucleic acid binding protein 2
Gene Symbol
NABP2
HGNC ID
HGNC:28412
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
636
Protein Name (eCommerce)
SOSS complex subunit B1
RefSeq ID
NM_024068
RefSeq Synonyms
NM_024068, BC006171, BC001079,
Research Areas
Cell Cycle,DNA Damage/Repair
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Single-stranded DNA -binding protein (SSB1) is phosphorylated by ATM in response to DNA damage. SSB1 is required for checkpoint activation and is critical for genomic stability.
UniGene ID
Hs.240170
UniProt ID (eCommerce)
Q9BQ15
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.