human NUPL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NUPL2.
shAAV-217266
AAV-h-NUPL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NUPL2 (nucleoporin like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CG1; H_RG271G13.9; hCG1; NLP_1; NLP-1; nucleoporin hCG1; nucleoporin-like protein 1; nucleoporin-like protein 2; NUP42 homolog
Description (eCommerce)
Nucleoporin-like protein 2 (NUPL2) is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15504].
Gene ID
11097
Gene Name (eCommerce)
nucleoporin like 2
Gene Name (Vector)
nucleoporin like 2
Gene Symbol
NUPL2
HGNC ID
HGNC:17010
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
Protein Name (eCommerce)
Nucleoporin-like protein 2
RefSeq ID
NM_007342
RefSeq Synonyms
NM_007342, BC107583, BC005327,
Research Areas
Cell Cycle,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,mRNA Processing,mRNA Transport,Ribonucleoprotein Transport,RNA Processing,RNA Transport,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism
Species
human
Target Sentence
Nucleoporin-like protein 2 (NUPL2) is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15504].
UniGene ID
Hs.408241
UniProt ID (eCommerce)
O15504
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.