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human NUDT4 shRNA silencing AAV

Name 
AAV-h-NUDT4-shRNA
Cat No 
shAAV-217218
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NUDT4.

shAAV-217218
AAV-h-NUDT4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NUDT4 (nudix hydrolase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DIPP2; DIPP2alpha; DIPP2beta; HDCMB47P
Description (Vector)
NUDT4 regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing.
Gene ID
11163
Gene Name (Vector)
nudix hydrolase 4
Gene Symbol
NUDT4
HGNC ID
HGNC:8051
ORF Size (aa)
543
RefSeq ID
NM_019094
RefSeq Synonyms
NM_199040, NM_019094, NM_001301024, NM_001301023, NM_001301022, BC051310, BC012069,
Species
human
UniGene ID
Hs.506325

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.