human NT5M shRNA silencing AAV

Name
AAV-h-NT5M-shRNA

Cat No
shAAV-217150

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NT5M.

shAAV-217150

AAV-h-NT5M-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NT5M (5′,3′-nucleotidase, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dNT-2; dNT2; mdN

Description (Vector)

NT5M encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene ID

56953

Gene Name (Vector)

5',3'-nucleotidase, mitochondrial

Gene Symbol

NT5M

HGNC ID

HGNC:15769

ORF Size (aa)

687

RefSeq ID

NM_020201

RefSeq Synonyms

NM_020201, BC035838,

Species

human

UniGene ID

Hs.513977

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.