human NSF shRNA silencing AAV

Name 
AAV-h-NSF-shRNA
Cat No 
shAAV-217112
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NSF.

shAAV-217112
AAV-h-NSF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; NEM-sensitive fusion protein; N-ethylmaleimide-sensitive factor-like protein; N-ethylmaleimide-sensitive fusion protein; SEC18; SKD2; vesicle-fusing ATPase; vesicular-fusion protein NSF
Description (eCommerce)
N-ethylmaleimide-sensitive fusion protein (NSF) is required for vesicle-mediated transport. It catalyzes the fusion of transport vesicles within the Golgi cisternae. It is also required for transport from the endoplasmic reticulum to the Golgi stack. NSF seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P46459].
Gene ID
4905
Gene Name (eCommerce)
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Gene Name (Vector)
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Gene Symbol
NSF
HGNC ID
HGNC:8016
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2235
ORF Size (bp)
2235 bp
Protein Name (eCommerce)
Vesicle-fusing ATPase
RefSeq ID
NM_006178
RefSeq Synonyms
NM_006178, BC030613,
Research Areas
BDNF Signaling,Golgi Apparatus,Neurobiology
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
N-ethylmaleimide-sensitive fusion protein (NSF) is required for vesicle-mediated transport. It catalyzes the fusion of transport vesicles within the Golgi cisternae. It is also required for transport from the endoplasmic reticulum to the Golgi stack. NSF seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P46459].
UniGene ID
Hs.431279
UniProt ID (eCommerce)
P46459

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.