human NRL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NRL.
shAAV-217086
AAV-h-NRL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NRL (neural retina leucine zipper). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D14S46E; NRL-MAF; RP27
Description (Vector)
NRL encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.
Gene ID
4901
Gene Name (Vector)
neural retina leucine zipper
Gene Symbol
NRL
HGNC ID
HGNC:8002
ORF Size (aa)
714
RefSeq ID
NM_006177
RefSeq Synonyms
NM_006177, BC012395,
Species
human
UniGene ID
Hs.652297
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.