human NR2E3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NR2E3.
shAAV-217048
AAV-h-NR2E3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NR2E3 (nuclear receptor subfamily 2 group E member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ESCS; PNR; rd7; RNR; RP37
Description (Vector)
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
10002
Gene Name (Vector)
nuclear receptor subfamily 2 group E member 3
Gene Symbol
NR2E3
HGNC ID
HGNC:7974
ORF Size (aa)
969
RefSeq ID
NM_014249
RefSeq Synonyms
NM_016346, NM_014249, BC041421,
Species
human
UniGene ID
Hs.187354
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.