human NPEPPS shRNA silencing AAV

Name 
AAV-h-NPEPPS-shRNA
Cat No 
shAAV-216952
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NPEPPS.

shAAV-216952
AAV-h-NPEPPS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NPEPPS (aminopeptidase puromycin sensitive). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AAP-S; MP100; PSA
Description (Vector)
NPEPPS encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
Gene ID
9520
Gene Name (Vector)
aminopeptidase puromycin sensitive
Gene Symbol
NPEPPS
HGNC ID
HGNC:7900
ORF Size (aa)
2628
ORF Size (bp)
2628 bp
RefSeq ID
NM_006310
RefSeq Synonyms
NM_006310, NM_001330257, BC065294,
Species
human
UniGene ID
Hs.443837

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.