human NOX1 shRNA silencing AAV

Name
AAV-h-NOX1-shRNA

Cat No
shAAV-216922

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NOX1.

shAAV-216922

AAV-h-NOX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOX1 (NADPH oxidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GP91-2; MOX1; NOH-1; NOH1

Description (Vector)

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

27035

Gene Name (Vector)

NADPH oxidase 1

Gene Symbol

NOX1

HGNC ID

HGNC:7889

ORF Size (aa)

1695

ORF Size (bp)

1695 bp

RefSeq ID

NM_007052

RefSeq Synonyms

NM_013955, NM_007052, NM_001271815, BC075015, BC075014,

Species

human

UniGene ID

Hs.592227

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.