human NOSIP shRNA silencing AAV

Name 
AAV-h-NOSIP-shRNA
Cat No 
shAAV-216908
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NOSIP.

shAAV-216908
AAV-h-NOSIP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOSIP (nitric oxide synthase interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-25; E3 ubiquitin-protein ligase NOSIP; eNOS-interacting protein; nitric oxide synthase-interacting protein; RING-type E3 ubiquitin transferase NOSIP
Description (eCommerce)
The protein encoded by the gene NOSIP, Nitric oxide synthase-interacting protein, may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production [taken from NCBI Entrez Gene (Gene ID: 51070)].
Description (Vector)
NOSIP may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein.
Gene ID
51070
Gene Name (eCommerce)
nitric oxide synthase interacting protein
Gene Name (Vector)
nitric oxide synthase interacting protein
Gene Symbol
NOSIP
HGNC ID
HGNC:17946
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
906
ORF Size (bp)
906 bp
Protein Name (eCommerce)
Nitric oxide synthase-interacting protein
RefSeq ID
NM_015953
RefSeq Synonyms
NM_015953, NM_001270960, BC011249, BC010077, BC009299,
Research Areas
Golgi Apparatus,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
The protein encoded by the gene NOSIP, Nitric oxide synthase-interacting protein, may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production [taken from NCBI Entrez Gene (Gene ID: 51070)].
UniGene ID
Hs.7236
UniProt ID (eCommerce)
Q9Y314

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.