human NOL6 shRNA silencing AAV

Name
AAV-h-NOL6-shRNA

Cat No
shAAV-216865

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NOL6.

shAAV-216865

AAV-h-NOL6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOL6 (nucleolar protein 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bA311H10.1; NRAP; UTP22

Description (Vector)

The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.

Gene ID

65083

Gene Name (Vector)

nucleolar protein 6

Gene Symbol

NOL6

HGNC ID

HGNC:19910

ORF Size (aa)

3432

ORF Size (bp)

3432 bp

RefSeq ID

NM_022917

RefSeq Synonyms

NM_139235, NM_022917, BC030139,

Species

human

UniGene ID

Hs.493709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.