human NKX6-1 shRNA silencing AAV

Name
AAV-h-NKX6-1-shRNA

Cat No
shAAV-216772

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NKX6-1.

shAAV-216772

AAV-h-NKX6-1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NKX6-1 (NK6 homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NKX6.1; NKX6A

Description (Vector)

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) (PubMed 15056733).(supplied by OMIM, Mar 2008)

Gene ID

4825

Gene Name (Vector)

NK6 homeobox 1

Gene Symbol

NKX6-1

HGNC ID

HGNC:7839

ORF Size (aa)

1104

ORF Size (bp)

1104 bp

RefSeq ID

NM_006168

RefSeq Synonyms

NM_006168, BC160030,

Species

human

UniGene ID

Hs.546270

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.