human NKX3-1 shRNA silencing AAV

Name 
AAV-h-NKX3-1-shRNA
Cat No 
shAAV-216767
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NKX3-1.

shAAV-216767
AAV-h-NKX3-1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NKX3-1 (NK3 homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BAPX2; NKX3; NKX3.1; NKX3A
Description (Vector)
NKX3-1 encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.
Gene ID
4824
Gene Name (Vector)
NK3 homeobox 1
Gene Symbol
NKX3-1
HGNC ID
HGNC:7838
ORF Size (aa)
705
RefSeq ID
NM_006167
RefSeq Synonyms
NM_006167, NM_001256339, BC074864, BC074863,
Species
human
UniGene ID
Hs.55999

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.