human NKD1 shRNA silencing AAV

Name
AAV-h-NKD1-shRNA

Cat No
shAAV-216750

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NKD1.

shAAV-216750

AAV-h-NKD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NKD1 (naked cuticle homolog 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Naked1

Description (Vector)

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.(supplied by OMIM, Jun 2003)

Gene ID

85407

Gene Name (Vector)

naked cuticle homolog 1

Gene Symbol

NKD1

HGNC ID

HGNC:17045

ORF Size (aa)

1413

ORF Size (bp)

1413 bp

RefSeq ID

NM_033119

RefSeq Synonyms

NM_033119, BC051288,

Species

human

UniGene ID

Hs.592059

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.