human NGF shRNA silencing AAV

Name
AAV-h-NGF-shRNA

Cat No
shAAV-216672

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NGF.

shAAV-216672

AAV-h-NGF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NGF (nerve growth factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Beta-NGF; HSAN5; NGFB

Description (Vector)

NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

Gene ID

4803

Gene Name (Vector)

nerve growth factor

Gene Symbol

NGF

HGNC ID

HGNC:7808

ORF Size (aa)

726

RefSeq ID

NM_002506

RefSeq Synonyms

NM_002506, BC126150, BC126148,

Species

human

UniGene ID

Hs.2561

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.