human NEK9 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NEK9.
shAAV-216578
AAV-h-NEK9-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NEK9 (NIMA related kinase 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APUG; LCCS10; NC; Nek8; NERCC; NERCC1; nercc1 kinase; Never in mitosis A-related kinase 9; NIMA (never in mitosis gene a)- related kinase 9; NimA-related kinase 8; nimA-related protein kinase 9; serine/threonine-protein kinase Nek9
Description (eCommerce)
NEK9 is a member of the NIMA-related serine/threonine kinases that play a role in mitotic progression. NEK9 plays a specific role in spindle organization and is necessary for accurate chromosome segregation. NEK9 may cooperate with the Ran-GTPase to regulate spindle formation. NEK6 and NEK7 are downstream substrates of NEK9 and may function cooperatively with NEK9 in mitotic spindle formation and maintenance.
Gene ID
91754
Gene Name (eCommerce)
NIMA related kinase 9
Gene Name (Vector)
NIMA related kinase 9
Gene Symbol
NEK9
HGNC ID
HGNC:18591
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2940
ORF Size (bp)
2940 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase Nek9
RefSeq ID
NM_033116
RefSeq Synonyms
NM_033116, NM_001329238, NM_001329237, BC112101, BC093881,
Research Areas
Cell Cycle,Cell Division,Kinase/Phosphatase,Mitochondrion
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
NEK9 is a member of the NIMA-related serine/threonine kinases that play a role in mitotic progression. NEK9 plays a specific role in spindle organization and is necessary for accurate chromosome segregation. NEK9 may cooperate with the Ran-GTPase to regulate spindle formation. NEK6 and NEK7 are downstream substrates of NEK9 and may function cooperatively with NEK9 in mitotic spindle formation and maintenance.
UniGene ID
Hs.7200
UniProt ID (eCommerce)
Q8TD19
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.