human NEK8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NEK8.
shAAV-216576
AAV-h-NEK8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NEK8 (NIMA related kinase 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
JCK; NEK12A; NPHP9; RHPD2
Description (Vector)
NEK8 encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.
Gene ID
284086
Gene Name (Vector)
NIMA related kinase 8
Gene Symbol
NEK8
HGNC ID
HGNC:13387
ORF Size (aa)
2079
ORF Size (bp)
2079 bp
RefSeq ID
NM_178170
RefSeq Synonyms
NM_178170, BC113705, BC112240,
Species
human
UniGene ID
Hs.448468
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.