human NEK7 shRNA silencing AAV

Name 
AAV-h-NEK7-shRNA
Cat No 
shAAV-216575
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEK7.

shAAV-216575
AAV-h-NEK7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEK7 (NIMA related kinase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
never in mitosis A-related kinase 7; NIMA (never in mitosis gene a)-related kinase 7; nimA-related protein kinase 7; serine/threonine-protein kinase Nek7
Description (eCommerce)
NEK7 [NIMA(never in mitosis gene a)-related kinase 7] is a member of the NIMA-related serine/threonine kinase family. NEK7 has been shown localize to spindle poles and to be required for mitotic spindle formation and cytokinesis.
Description (Vector)
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.(supplied by OMIM, Jul 2002)
Gene ID
140609
Gene Name (eCommerce)
NIMA related kinase 7
Gene Name (Vector)
NIMA related kinase 7
Gene Symbol
NEK7
HGNC ID
HGNC:13386
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
906
ORF Size (bp)
906 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase Nek7
RefSeq ID
NM_133494
RefSeq Synonyms
NM_133494, BC156616, BC152872,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
NEK7 [NIMA(never in mitosis gene a)-related kinase 7] is a member of the NIMA-related serine/threonine kinase family. NEK7 has been shown localize to spindle poles and to be required for mitotic spindle formation and cytokinesis.
UniGene ID
Hs.24119
UniProt ID (eCommerce)
Q8TDX7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.