human NDUFS7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NDUFS7.
shAAV-216531
AAV-h-NDUFS7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CI-20; CI-20KD; MY017; PSST
Description (Vector)
NDUFS7 encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
Gene ID
374291
Gene Name (Vector)
NADH:ubiquinone oxidoreductase core subunit S7
Gene Symbol
NDUFS7
HGNC ID
HGNC:7714
ORF Size (aa)
642
RefSeq ID
NM_024407
RefSeq Synonyms
NM_024407, BC111517, BC005954,
Species
human
UniGene ID
Hs.211914
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.