human NDUFS3 shRNA silencing AAV

Name
AAV-h-NDUFS3-shRNA

Cat No
shAAV-216525

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NDUFS3.

shAAV-216525

AAV-h-NDUFS3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CI-30

Description (Vector)

NDUFS3 encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

Gene ID

4722

Gene Name (Vector)

NADH:ubiquinone oxidoreductase core subunit S3

Gene Symbol

NDUFS3

HGNC ID

HGNC:7710

ORF Size (aa)

795

RefSeq ID

NM_004551

RefSeq Synonyms

NM_004551, BC000617,

Species

human

UniGene ID

Hs.502528

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.