human NDUFB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NDUFB3.
shAAV-216506
AAV-h-NDUFB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NDUFB3 (NADH:ubiquinone oxidoreductase subunit B3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B12; CI-B12
Description (Vector)
NDUFB3 encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene.
Gene ID
4709
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit B3
Gene Symbol
NDUFB3
HGNC ID
HGNC:7698
ORF Size (aa)
297
RefSeq ID
NM_002491
RefSeq Synonyms
NM_002491, NM_001257102, BC018183,
Species
human
UniGene ID
Hs.109760
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.