human NDUFB2 shRNA silencing AAV

Name
AAV-h-NDUFB2-shRNA

Cat No
shAAV-216505

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NDUFB2.

shAAV-216505

AAV-h-NDUFB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AGGG; CI-AGGG

Description (Vector)

NDUFB2 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I.

Gene ID

4708

Gene Name (Vector)

NADH:ubiquinone oxidoreductase subunit B2

Gene Symbol

NDUFB2

HGNC ID

HGNC:7697

ORF Size (aa)

288

RefSeq ID

NM_004546

RefSeq Synonyms

NM_004546, BC063026,

Species

human

UniGene ID

Hs.655788

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.