human NDUFAF3 shRNA silencing AAV

Name
AAV-h-NDUFAF3-shRNA

Cat No
shAAV-216497

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NDUFAF3.

shAAV-216497

AAV-h-NDUFAF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2P1; C3orf60; E3-3

Description (Vector)

NDUFAF3 encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

25915

Gene Name (Vector)

NADH:ubiquinone oxidoreductase complex assembly factor 3

Gene Symbol

NDUFAF3

HGNC ID

HGNC:29918

ORF Size (aa)

555

RefSeq ID

NM_199069

RefSeq Synonyms

NM_199074, NM_199073, NM_199070, NM_199069, BC111004, BC002873,

Species

human

UniGene ID

Hs.31387

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.