human NDUFA2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NDUFA2.
shAAV-216476
AAV-h-NDUFA2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B8; CD14; CIB8
Description (Vector)
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.
Gene ID
4695
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit A2
Gene Symbol
NDUFA2
HGNC ID
HGNC:7685
ORF Size (aa)
300
RefSeq ID
NM_002488
RefSeq Synonyms
NM_002488, NM_001185012, BC003674,
Species
human
UniGene ID
Hs.534333
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.