human NCR1 shRNA silencing AAV

Name 
AAV-h-NCR1-shRNA
Cat No 
shAAV-216430
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NCR1.

shAAV-216430
AAV-h-NCR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NCR1 (natural cytotoxicity triggering receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD335;CD335;hNKp46;LY94;Lymphocyte antigen 94 homolog;lymphocyte antigen 94 homolog (activating NK-receptor);natural cytotoxicity triggering receptor 1;natural killer cell p46-related protein;NK cell-activating receptor;NKP46;NK-p46
Description (eCommerce)
NCR1/NKp46 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O76036].
Gene ID
9437
Gene Name (eCommerce)
natural cytotoxicity triggering receptor 1
Gene Name (Vector)
natural cytotoxicity triggering receptor 1
Gene Symbol
NCR1
HGNC ID
HGNC:6731
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
912
ORF Size (bp)
912 bp
Protein Name (eCommerce)
Natural cytotoxicity triggering receptor 1
RefSeq ID
NM_004829
RefSeq Synonyms
NM_004829, NM_001242357, NM_001242356, NM_001145458, NM_001145457, BC064806,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
NCR1/NKp46 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O76036].
UniGene ID
Hs.97084
UniProt ID (eCommerce)
O76036

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.