human NCLN shRNA silencing AAV

Name 
AAV-h-NCLN-shRNA
Cat No 
shAAV-216412
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NCLN.

shAAV-216412
AAV-h-NCLN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NCLN (nicalin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NET59; nicalin; nicalin homolog; nicastrin-like protein
Description (eCommerce)
Nicastrin-like protein (NCLN) may antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q969V3].
Gene ID
56926
Gene Name (eCommerce)
nicalin
Gene Name (Vector)
nicalin
Gene Symbol
NCLN
HGNC ID
HGNC:26923
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1692
ORF Size (bp)
1692 bp
Protein Name (eCommerce)
Nicalin
RefSeq ID
NM_020170
RefSeq Synonyms
NM_020170, NM_001321463, BC025926, BC019091, BC013283, BC010064,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Nicastrin-like protein (NCLN) may antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q969V3].
UniGene ID
Hs.657032
UniProt ID (eCommerce)
Q969V3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.