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human NCKAP1 shRNA silencing AAV

Name 
AAV-h-NCKAP1-shRNA
Cat No 
shAAV-216403
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NCKAP1.

shAAV-216403
AAV-h-NCKAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NCKAP1 (NCK associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HEM2; membrane-associated protein HEM-2; NAP 1; NAP1; NAP125; nck-associated protein 1; p125Nap1
Description (eCommerce)
Nck-associated protein 1 is encoded for by the gene NCKAP1, also known as NAP125. Nck-associated protein 1 is part of the WAVE complex that regulates actin filament reorganization and lamellipodia formation [taken from NCBI Entrez Gene (Gene ID: 10787)].
Gene ID
10787
Gene Name (eCommerce)
NCK associated protein 1
Gene Name (Vector)
NCK associated protein 1
Gene Symbol
NCKAP1
HGNC ID
HGNC:7666
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3387
ORF Size (bp)
3387 bp
Protein Name (eCommerce)
Nck-associated protein 1
RefSeq ID
NM_013436
RefSeq Synonyms
NM_205842, NM_013436, BC015025,
Research Areas
Apoptosis,Cardiac Development,Cardiology,Cardiovascular,Cytoskeleton,Immunology,Innate Immunity,Neurobiology,Neurodevelopment,PDGF Signaling,RAC1 Signaling,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Nck-associated protein 1 is encoded for by the gene NCKAP1, also known as NAP125. Nck-associated protein 1 is part of the WAVE complex that regulates actin filament reorganization and lamellipodia formation [taken from NCBI Entrez Gene (Gene ID: 10787)].
UniGene ID
Hs.603732
UniProt ID (eCommerce)
Q9Y2A7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.