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human NCK2 shRNA silencing AAV

Name 
AAV-h-NCK2-shRNA
Cat No 
shAAV-216401
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NCK2.

shAAV-216401
AAV-h-NCK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NCK2 (NCK adaptor protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GRB4; NCKbeta
Description (Vector)
NCK2 encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
8440
Gene Name (Vector)
NCK adaptor protein 2
Gene Symbol
NCK2
HGNC ID
HGNC:7665
ORF Size (aa)
1143
ORF Size (bp)
1143 bp
RefSeq ID
NM_003581
RefSeq Synonyms
NM_003581, NM_001004722, NM_001004720, BC007195, BC000103,
Species
human
UniGene ID
Hs.707062

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.