human NCAPD2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NCAPD2.
shAAV-216382
AAV-h-NCAPD2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NCAPD2 (non-SMC condensin I complex subunit D2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAP-D2; chromosome condensation-related SMC-associated protein 1; chromosome-associated protein D2; CNAP1; condensin complex subunit 1; hCAP-D2; MCPH21; Non-SMC condensin I complex subunit D2; XCAP-D2 homolog
Description (eCommerce)
CAP-D2 is a subunit of the heteropentameric condensin I complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. In the condensin complex CAP-D2 may be important for targeting condensin to mitotic chromosomes as well as metaphase alignment of sister chromatids.
Gene ID
9918
Gene Name (eCommerce)
non-SMC condensin I complex subunit D2
Gene Name (Vector)
non-SMC condensin I complex subunit D2
Gene Symbol
NCAPD2
HGNC ID
HGNC:24305
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4206
ORF Size (bp)
4206 bp
Protein Name (eCommerce)
Condensin complex subunit 1
RefSeq ID
NM_014865
RefSeq Synonyms
NM_014865, BC028182,
Research Areas
Cell Cycle,Cell Division,Histone Modification,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CAP-D2 is a subunit of the heteropentameric condensin I complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. In the condensin complex CAP-D2 may be important for targeting condensin to mitotic chromosomes as well as metaphase alignment of sister chromatids.
UniGene ID
Hs.5719
UniProt ID (eCommerce)
Q15021
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.