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human NAV1 shRNA silencing AAV

Name 
AAV-h-NAV1-shRNA
Cat No 
shAAV-216357
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NAV1.

shAAV-216357
AAV-h-NAV1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NAV1 (neuron navigator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
POMFIL3; STEERIN1; UNC53H1
Description (Vector)
NAV1 belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. NAV1 is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
Gene ID
89796
Gene Name (Vector)
neuron navigator 1
Gene Symbol
NAV1
HGNC ID
HGNC:15989
ORF Size (aa)
5622
ORF Size (bp)
5622 bp
RefSeq ID
NM_020443
RefSeq Synonyms
NM_020443, NM_001167738, BC172534, BC156464, BC007523,
Species
human
UniGene ID
Hs.585374

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.