human NAPSA shRNA silencing AAV

Name
AAV-h-NAPSA-shRNA

Cat No
shAAV-216320

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NAPSA.

shAAV-216320

AAV-h-NAPSA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NAPSA (napsin A aspartic peptidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KAP; Kdap; NAP1; NAPA; SNAPA

Description (Vector)

The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.

Gene ID

9476

Gene Name (Vector)

napsin A aspartic peptidase

Gene Symbol

NAPSA

HGNC ID

HGNC:13395

ORF Size (aa)

1263

ORF Size (bp)

1263 bp

RefSeq ID

NM_004851

RefSeq Synonyms

NM_004851, BC017842,

Species

human

UniGene ID

Hs.714418

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.