human MYL12B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MYL12B.
shAAV-216180
AAV-h-MYL12B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MYL12B (myosin light chain 12B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MLC-B; MRLC2
Description (Vector)
The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 (PubMed 11942626)).(supplied by OMIM, Mar 2008)
Gene ID
103910
Gene Name (Vector)
myosin light chain 12B
Gene Symbol
MYL12B
HGNC ID
HGNC:29827
ORF Size (aa)
519
RefSeq ID
NM_033546
RefSeq Synonyms
NM_033546, NM_001144945, NM_001144944, BC004994,
Species
human
UniGene ID
Hs.464472
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.