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human MVD shRNA silencing AAV

Name 
AAV-h-MVD-shRNA
Cat No 
shAAV-216093
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MVD.

shAAV-216093
AAV-h-MVD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MVD (mevalonate diphosphate decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FP17780; MDDase; MPD; POROK7
Description (Vector)
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
Gene ID
4597
Gene Name (Vector)
mevalonate diphosphate decarboxylase
Gene Symbol
MVD
HGNC ID
HGNC:7529
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
RefSeq ID
NM_002461
RefSeq Synonyms
NM_002461, BC000011,
Species
human
UniGene ID
Hs.252457

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.