human MTRF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MTRF1.
shAAV-216047
AAV-h-MTRF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MTRF1 (mitochondrial translation release factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MRF1; MTTRF1; RF1
Description (Vector)
MTRF1 was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear.
Gene ID
9617
Gene Name (Vector)
mitochondrial translation release factor 1
Gene Symbol
MTRF1
HGNC ID
HGNC:7469
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_004294
RefSeq Synonyms
NM_004294, BC042196, BC027731,
Species
human
UniGene ID
Hs.382176
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.