human MTO1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MTO1.
shAAV-216035
AAV-h-MTO1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MTO1 (mitochondrial tRNA translation optimization 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-02; COXPD10
Description (Vector)
MTO1 encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
25821
Gene Name (Vector)
mitochondrial tRNA translation optimization 1
Gene Symbol
MTO1
HGNC ID
HGNC:19261
ORF Size (aa)
2079
ORF Size (bp)
2079 bp
RefSeq ID
NM_012123
RefSeq Synonyms
NM_133645, NM_012123, NM_001123226, BC011051,
Species
human
UniGene ID
Hs.347614
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.